DESIGN
- Design structure projects for experimental success
- Incorporate wider scientific context & goals of project team
- Leverage broad drug discovery experience
- Provide scientific & strategic value
Structural Biology Consulting
Opilio helps companies harness the value of structural biology efficiently and economically.
ABOUT
Jeremiah Joseph, Founder
Opilio (ōpiliō, Latin for "shepherd"), was founded in 2023, with a vision to help companies harness the value of structural biology efficiently and economically.
Structural biology powerfully provides concrete visuals: how a small molecule engages its protein target, how an antibody binds its cognate antigen, how biomolecular complexes assemble. These pictures can stimulate scientific creativity, support confident decision making, and fast-track projects.
Opilio's founder, Jeremiah Joseph, has over 25 years of post-PhD experience, spanning structural biology, protein science, in vitro pharmacology, and management (people/data/projects/CROs) - all this acquired in pharma, biotech, and academia.
Opilio offers his on-demand expertise to manage and enable in-house and outsourced projects on a fractional FTE basis: a cost-effective, win-win arrangement that keeps critical IP closer to home.
Services
DRIVE
- Manage in-house & outsourced gene-to-structure projects
- Handle CRO interactions: expert point of contact between project team & CRO
- Troubleshoot all steps from construct design to data collection
- Enable progress with hands-on structure data analysis (processing, solution, refinement)
DELIVER
- Diffract, solve & refine crystal structures; build & refine cryoEM structures
- Communicate results with holistic project context
- Limit external exposure of critical IP (identity of protein targets & ligands)
- Provide efficient & economical service through fractional FTE model
Resources
Quick access to Opilio-hosted resources.
Contact
Opilio LLC
Structural Biology Consulting